What is the likelihood for ongoing seizures in children without an apparent cause for their particular epilepsy?
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The main aim of this study was to determine what factors predict the seizure outcome of children with epilepsy.
When do children diagnosed with epilepsy continue to have seizures over the long-term?
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The main aim of this study was to determine seizure status of children 2 to 17 years of age diagnosed with epilepsy.
Understanding adolescent- onset epilepsy and the risks involved
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The authors of this study found a variety of reasons why some patients continued to experience seizures after treatment, or required prolonged use of medication to treat seizures.
How do adolescents with epilepsy view their quality of life?
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The primary aim of this study was to gain a greater understanding of how children and adolescents with epilepsy (specifically, epilepsy that does not respond to medical treatment) perceive their quality of life.
Some cases of complex partial epilepsy (CPE) are unresponsive to a single drug treatment
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Complex partial epilepsy (CPE) is a developmental disorder defined by recurrent seizures that are localized to one part of the brain and can impair consciousness or awareness
Epileptic seizures may promote spinal cord injuries in patients with spinal instrumentation for scoliosis
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Beyond the effects of seizures, spinal instrumentation inserted surgically to treat scoliosis may add pressure to the spine, making injuries even more likely.
Readily available clinical indicators may predict risk of adverse outcome in asphyxiated newborns who experience seizures
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Perinatal asphyxia in newborns can lead to a range of disorders including cerebral palsy, intellectual disability, global developmental delay, or epilepsy.
New scoring system may help doctors to predict future neurological deficits in newborns who experience seizures
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A scoring system based on certain risk-factors that predispose newborns experiencing seizures to long-term developmental disability will help doctors to identify patients who will benefit from early treatment.
Topiromate may be effective for treating seizures in newborns
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Topiramate, approved by the Food and Drug Administration (FDA) for use in children older than two years of age, has been shown to be effective for treating seizures, and, moreover, it seems to protect the brain from injury.
Gene duplications may play a role in developmental disorders with autism-like characteristics
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Genetic duplications or deletions may exist even in patients with normal karyotypes, and these variations may play an explanatory role in a patient’s autism-like characteristics.
One case of extreme prematurity suggests a possible link between cerebellar injury and autism spectrum disorders
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As more preterm survivors of cerebellar injury are monitored for long-term development, physicians will be able to more readily evaluate potential risk for ASD associated with extreme prematurity and cerebellar injury.
Further insights into the genetic causes of autism spectrum disorders
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Continuing investigations will help to draw links between particular CNVs and developmental symptoms, enabling improved genetic testing and counselling, and more targeted treatment.