Injury to the cerebellum in premature infants can be accompanied by region-specific impairments to cerebral growth

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Brain development accelerates rapidly during the third trimester of gestation, and infants born before this process are vulnerable to brain injury. This injury can affect neurodevelopment, impairing later motor, social, behavioral, cognitive, and language abilities. Improved early detection of brain injuries and a deeper understanding of their full extent will allow practitioners to develop valuable therapies for improving long-term outcomes among preterm infants.

Increased blood flow to the brain following asphyxiation may predict a newborn’s risk for brain injury

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This study shows us that perfusion rate following asphyxiation does influence the extent of brain injury that leads to neurological deficits in high-risk newborns. Hypothermia is currently the only effective treatment for minimizing neurological deficits in high-risk newborns following asphyxiation. It is thought that hypothermia therapy prevents reperfusion injury by slowing the cascade of events that lead to cell death.

The important distinction between hemophagocytic lymphohistiocytosis and enteroviral infection

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Enteroviral infection is the most frequently diagnosed viral infection among newborns and is treated according to its severity. Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disorder of an exaggerated immune response, treated with chemotherapy or immunosuppressive agents. Because HLH is so rare, it should only be diagnosed with great care in newborn patients displaying enteroviral infection

A new scoring system can help doctors predict future neurological deficits in newborns who experience seizures

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Medical advances have allowed more newborns experiencing seizures to survive into adulthood than ever before. Early identification of children likely to develop developmental disorders following neonatal seizures will allow for early treatment, which can minimize eventual cognitive and motor delays.

Removing Barriers for Youth with Physical Disabilities Increases Participation

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This study aimed to gain more insight into the effectiveness of altering the environment in which youth with physical disabilities participate in leisurely activities in Quebec.

Benefits and drawbacks of using genomic discoveries for autism spectrum disorder

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This article is a summary of significant advances in evidence-based practices related to ASD diagnosis, characterization, and treatment. It includes a discussion on the scientific, ethical, policy, and communication aspects of translating new discoveries into clinical and diagnostic tools.

Sensori-motor performance and daily living skills in preschool children with autism

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Early interventions that address sensory and motor development may facilitate a child’s integration into daycare programs and schools and ease the burden of care for parents.

The ASD Demonstration Project: A multi-center study to expand our understanding of ASD

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NeuroDevNet hopes that the ASD Demonstration Project will improve clinical care and the daily lives of individuals with ASD and their families by promoting earlier diagnoses, concrete prognoses, and individually targeted treatments.

Identifying new genetic markers associated with autism spectrum disorders

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This study adds 6 potential target loci to the list of genetic mutations that are associated with ASD. Continuing study of important genetic markers will help scientists develop earlier outcome prediction and therapeutic intervention in children with ASDs.

Mutations in the foxp1 gene may be associated with language impairments that accompany intellectual disability and autism

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The FOXP1 and FOXP2 genes provide interesting genetic targets for further investigation into the molecular mechanisms underlying neurodevelopmental disorders like intellectual disability, ASD, and language impairment.

Can administrative databases such as the RAMQ be used to identify children with traumatic brain injury?

Learn about Traumatic Brain Injury

Combining patient information into a physician billing claim data-base (the ramq database), which is readily available, may be a valid method of estimating injury occurrence among children.

Do children who sustain a mild traumatic brain injury lose confidence in returning to physical activity?

Learn about Traumatic Brain Injury

Some children, after a mild traumatic brain injury, appear to lack confidence in their ability to perform well during physical activities as compared to before their injury. This occurs even though the children are still participating in physical activities at comparable levels to before injury.

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